Grant opportunity

Palliative Care Research Across the Lifespan: Leveraging the Palliative Care Consortium (R01 Clinical Trial Optional)

The purpose of this Notice of Funding Opportunity (NOFO) is to invite R01 applications proposing research on palliative care across the lifespan for persons with serious illnesses and/or their care partners relevant to the missions of participating NIH Institutes, Centers, and Offices (ICOs), including projects focused on palliative care access, use, and quality. Applications may propose hypothesis-driven, milestone-defined palliative care traditional efficacy (Stage II), real-world efficacy (Stage III), effectiveness (Stage IV), and/or dissemination and implementation (Stage V) clinical trials in alignment with the NIH Stage Model (Stages II-V) and relevant Institute or Center policies. Applications may propose non-clinical trial palliative care research, such as health services research, methodologic research, natural experiments, or observational studies. Recipients will become members of the research community facilitated by the NIH-funded Advancing the Science of Palliative Care Across the Lifespan (ASCENT) Consortium. NOTE : This NOFO is not appropriate for applications proposing new intervention generation, refinement, modification, adaptation, and/or pilot testing (Stage I of the NIH Stage Model) clinical trial research. The intervention(s) to be tested must be in a developed and testable form, with Stage I activities already completed and demonstrated.

GrantHealth and Biomedical SciencesUnited StatesNational Institutes of HealthGrants.gov
Funder
National Institutes of Health
Applications close 2029-11-05
Applications close 2029-11-05: Nov 5, 2029
Award
See official notice
Applicant
City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; State governments; Native American tribal governments (Federally recognized); Public and State controlled institutions of higher education; County governments; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Public housing authorities/Indian housing authorities; Independent school districts
Discipline
Health and Biomedical Sciences
Region
United States
Posted
Oct 27, 2026

Call summary

Overview

Palliative Care Research Across the Lifespan: Leveraging the Palliative Care Consortium (R01 Clinical Trial Optional) is an official Grants.gov notice published between 30 September and 27 October 2026. Opportunity number: PAR-27-090

Who can apply

Eligible applicant types listed by the agency: City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; State governments; Native American tribal governments (Federally recognized); Public and State controlled institutions of higher education; County governments; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Public housing authorities/Indian housing authorities; Independent school districts. Applicants must also satisfy every programme-specific condition in the official notice.

What it supports

  • The purpose of this Notice of Funding Opportunity (NOFO) is to invite R01 applications proposing research on palliative care across the lifespan for persons with serious illnesses and/or their care partners relevant to the missions of participating NIH Institutes, Centers, and Offices (ICOs), including projects focused on palliative care access, use, and quality. Applications may propose hypothesis-driven, milestone-defined palliative care traditional efficacy (Stage II), real-world efficacy (Stage III), effectiveness (Stage IV), and/or dissemination and implementation (Stage V) clinical trials in alignment with the NIH Stage Model (Stages II-V) and relevant Institute or Center policies. Applications may propose non-clinical trial palliative care research, such as health services research, methodologic research, natural experiments, or observational studies. Recipients will become members of the research community facilitated by the NIH-funded Advancing the Science of Palliative Care Across the Lifespan (ASCENT) Consortium. NOTE : This NOFO is not appropriate for applications proposing new intervention generation, refinement, modification, adaptation, and/or pilot testing (Stage I of the NIH Stage Model) clinical trial research. The intervention(s) to be tested must be in a developed and testable form, with Stage I activities already completed and demonstrated.
  • Opportunity number: PAR-27-090

Funding and duration

  • Award ceiling: See official notice

Applications close 2029-11-05

Applications close 2029-11-05: Nov 5, 2029

How to apply

Open the official Grants.gov record, review the full notice and attachments, and use the application package or agency route stated there.

Call details

Source-based overview

The purpose of this Notice of Funding Opportunity (NOFO) is to invite R01 applications proposing research on palliative care across the lifespan for persons with serious illnesses and/or their care partners relevant to the missions of participating NIH Institutes, Centers, and Offices (ICOs), including projects focused on palliative care access, use, and quality. Applications may propose hypothesis-driven, milestone-defined palliative care traditional efficacy (Stage II), real-world efficacy (Stage III), effectiveness (Stage IV), and/or dissemination and implementation (Stage V) clinical trials in alignment with the NIH Stage Model (Stages II-V) and relevant Institute or Center policies. Applications may propose non-clinical trial palliative care research, such as health services research, methodologic research, natural experiments, or observational studies. Recipients will become members of the research community facilitated by the NIH-funded Advancing the Science of Palliative Care Across the Lifespan (ASCENT) Consortium. NOTE : This NOFO is not appropriate for applications proposing new intervention generation, refinement, modification, adaptation, and/or pilot testing (Stage I of the NIH Stage Model) clinical trial research. The intervention(s) to be tested must be in a developed and testable form, with Stage I activities already completed and demonstrated. The official record contains the controlling eligibility, budget, attachment and submission requirements for opportunity PAR-27-090.

Eligibility

Eligible applicant types listed by the agency: City or township governments; Native American tribal organizations (other than Federally recognized tribal governments); For profit organizations other than small businesses; State governments; Native American tribal governments (Federally recognized); Public and State controlled institutions of higher education; County governments; Private institutions of higher education; Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Public housing authorities/Indian housing authorities; Independent school districts. Applicants must also satisfy every programme-specific condition in the official notice.

Funding and benefits

Award ceiling: See official notice

Themes and supported activities

The purpose of this Notice of Funding Opportunity (NOFO) is to invite R01 applications proposing research on palliative care across the lifespan for persons with serious illnesses and/or their care partners relevant to the missions of participating NIH Institutes, Centers, and Offices (ICOs), including projects focused on palliative care access, use, and quality. Applications may propose hypothesis-driven, milestone-defined palliative care traditional efficacy (Stage II), real-world efficacy (Stage III), effectiveness (Stage IV), and/or dissemination and implementation (Stage V) clinical trials in alignment with the NIH Stage Model (Stages II-V) and relevant Institute or Center policies. Applications may propose non-clinical trial palliative care research, such as health services research, methodologic research, natural experiments, or observational studies. Recipients will become members of the research community facilitated by the NIH-funded Advancing the Science of Palliative Care Across the Lifespan (ASCENT) Consortium. NOTE : This NOFO is not appropriate for applications proposing new intervention generation, refinement, modification, adaptation, and/or pilot testing (Stage I of the NIH Stage Model) clinical trial research. The intervention(s) to be tested must be in a developed and testable form, with Stage I activities already completed and demonstrated.

Opportunity number: PAR-27-090

Deadline and timeline

Applications close 2029-11-05: Applications close 2029-11-05: Nov 5, 2029.

Applicants should confirm the exact deadline time, time zone, required documents, portal steps and any institutional approvals on the official call page before submitting.

How to apply

Open the official Grants.gov record, review the full notice and attachments, and use the application package or agency route stated there.

Before applying, check eligibility rules, budgets, attachments, page limits, partner requirements, cost-share conditions and whether the opportunity uses an expression of interest, full proposal, registration or nomination stage.