Grant opportunity
Open Competition: Implementation of Findings From PCORI's Research Investments -- Cycle 3 2026
PCORI pre-announcement for implementation projects that move selected PCORI-funded evidence into practical use to improve health care and outcomes.
- Funder
- Patient-Centered Outcomes Research Institute (PCORI)
- LOI deadline
- LOI deadline: Sep 8, 2026
- Award
- Up to USD 1.8 million direct costs
- Applicant
- Research Team
- Discipline
- Health & Biomedical Sciences
- Region
- United States
- Posted
- May 16, 2026
Call summary
Overview
PCORI intends to release an open competition implementation PFA for projects that promote uptake of selected peer-reviewed findings from PCORI-funded patient-centered comparative clinical effectiveness research.
Who can apply
- Implementation experts, principal investigators, patients, and stakeholder partners may propose projects; applicants do not have to have been associated with the original PCORI-funded studies.
- Applicants must focus on the eligible evidence areas identified for the Cycle 3 2026 PFA.
What it supports
- Implementation projects that adapt, scale up, or scale out selected PCORI evidence in health systems and other real-world contexts.
- Projects should include a rigorous evaluation plan and demonstrate commitment and buy-in from implementation sites and relevant stakeholder organisations.
Funding and duration
Applicants may propose budgets up to USD 1.8 million in total direct costs, with project periods up to four years.
LOI deadline
LOI deadline: Sep 8, 2026
How to apply
Use the official PCORI announcement page. The PFA opens on 4 August 2026, the LOI deadline is 8 September 2026 at 5:00 pm ET, and invited applications are due 12 January 2027.
Call details
About the opportunity
This is a pre-announcement. Use it for early planning and return to the official page when the full application package or portal opens.
PCORI intends to release an open competition implementation PFA for projects that promote uptake of selected peer-reviewed findings from PCORI-funded patient-centered comparative clinical effectiveness research.
Patient-Centered Outcomes Research Institute (PCORI) lists this opportunity for Research Team, Health & Biomedical Sciences, United States.
This listing is written for researchers, students, universities, NGOs, research teams, policy professionals and academic institutions searching for Health & Biomedical Sciences grants, fellowships, scholarships, conferences, workshops and funding opportunities in United States contexts.
Eligibility
Implementation experts, principal investigators, patients, and stakeholder partners may propose projects; applicants do not have to have been associated with the original PCORI-funded studies.
Applicants must focus on the eligible evidence areas identified for the Cycle 3 2026 PFA.
Funding and benefits
Applicants may propose budgets up to USD 1.8 million in total direct costs, with project periods up to four years.
Themes and supported activities
Implementation projects that adapt, scale up, or scale out selected PCORI evidence in health systems and other real-world contexts.
Projects should include a rigorous evaluation plan and demonstrate commitment and buy-in from implementation sites and relevant stakeholder organisations.
Deadline and timeline
LOI deadline: LOI deadline: Sep 8, 2026.
Applicants should confirm the exact deadline time, time zone, required documents, portal steps and any institutional approvals on the official call page before submitting.
How to apply
Use the official PCORI announcement page. The PFA opens on 4 August 2026, the LOI deadline is 8 September 2026 at 5:00 pm ET, and invited applications are due 12 January 2027.
Before applying, check eligibility rules, budgets, attachments, page limits, partner requirements, cost-share conditions and whether the opportunity uses an expression of interest, full proposal, registration or nomination stage.