Digital Health Technology and Reciprocal Innovation to Improve Clinical and Public Health Outcomes

Source-based overview

This initiative will support research on the development, validation, feasibility, and effectiveness of innovative digital health interventions or tools (including mobile health) specifically suited for underserved settings in the U.S. and globally. Research should utilize new or emerging technologies, platforms, systems, and/or analytics to address high priority health problems, expand the evidence base for the use of digital health technology to improve clinical and public health outcomes, and strengthen research collaborations between U.S. and low- and middle-income country (LMIC) researchers. Applications must include reciprocal innovation methodologies – bidirectional and iterative exchange of ideas, resources, and innovation approaches to address shared health challenges in the U.S. and a LMIC. Through this utilization of unique data, environments, and populations in domestic and international contexts, awards will maximize generalizable knowledge produced and optimize potential benefit to U.S. and LMIC populations.

Eligibility

For profit organizations other than small businesses; Private institutions of higher education; Public housing authorities/Indian housing authorities; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Independent school districts; Special district governments; City or township governments. Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Funding and benefits

Amount varies by notice and award terms

Themes and supported activities

Health and Biomedical Sciences

Global / international

Grant

Deadline and timeline

Estimated application due date: 2027-02-11: Estimated application due date: 2027-02-11: Feb 11, 2027.

Applicants should confirm the exact deadline time, time zone, required documents, portal steps and any institutional approvals on the official call page before submitting.

How to apply

Open the linked Grants.gov listing to review the full package, attachments, eligibility rules, deadline time zone and submission route.

Before applying, check eligibility rules, budgets, attachments, page limits, partner requirements, cost-share conditions and whether the opportunity uses an expression of interest, full proposal, registration or nomination stage.