Grant opportunity
PRISM Call for Paediatric Multinational Investigator-Initiated Clinical Studies
Advance notice of support for multinational paediatric pragmatic trials, optimisation or repurposing studies, and observational studies conducted across Europe and Canada.
- Funder
- Paediatric Clinical Research Infrastructure Service Model (PRISM)
- Pre-announcement: call expected in mid-September 2026; letters of intent expected by mid-December 2026
- Pre-announcement: call expected in mid-September 2026; letters of intent expected by mid-December 2026
- Award
- Selected studies receive investigation and coordination funding plus multinational trial-management services
- Applicant
- Investigator-led multinational paediatric studies planned across three to six countries in Europe and Canada; cancer and rare-disease studies are excluded.
- Discipline
- Paediatric and Clinical Research
- Region
- Europe and Canada
- Posted
- Aug 18, 2026
Call summary
Overview
PRISM will select pilot investigator-initiated paediatric studies and provide end-to-end infrastructure and expertise for planning and conducting multinational research.
Who can apply
Projects should be investigator initiated, involve three to six countries in Europe and Canada, and fall within the eligible paediatric study designs. Cancer and rare-disease projects are outside this call.
What it supports
- Pragmatic comparative-effectiveness trials
- Optimisation and repurposing studies
- Observational studies
- Multinational paediatric research
Funding and duration
- Investigation and trial-coordination costs for selected studies
- Multinational trial-management services from the PRISM consortium
Pre-announcement: call expected in mid-September 2026; letters of intent expected by mid-December 2026
Pre-announcement: call expected in mid-September 2026; letters of intent expected by mid-December 2026
How to apply
Use the pre-announcement for planning and return to the official PRISM page when the call and letter-of-intent instructions are released.
Call details
Source-based overview
The planned two-stage call will first invite letters of intent. Shortlisted teams will receive design and planning support before full applications are assessed for investigation funding and coordinated multinational trial services.
Eligibility
Projects should be investigator initiated, involve three to six countries in Europe and Canada, and fall within the eligible paediatric study designs. Cancer and rare-disease projects are outside this call.
Funding and benefits
Investigation and trial-coordination costs for selected studies
Multinational trial-management services from the PRISM consortium
Themes and supported activities
Pragmatic comparative-effectiveness trials
Optimisation and repurposing studies
Observational studies
Multinational paediatric research
Deadline and timeline
Pre-announcement: call expected in mid-September 2026; letters of intent expected by mid-December 2026: Pre-announcement: call expected in mid-September 2026; letters of intent expected by mid-December 2026.
Applicants should confirm the exact deadline time, time zone, required documents, portal steps and any institutional approvals on the official call page before submitting.
How to apply
Use the pre-announcement for planning and return to the official PRISM page when the call and letter-of-intent instructions are released.
Before applying, check eligibility rules, budgets, attachments, page limits, partner requirements, cost-share conditions and whether the opportunity uses an expression of interest, full proposal, registration or nomination stage.