Grant opportunity

HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)

National Institutes of Health has posted HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional), a health and biomedical sciences funding opportunity listed on Grants.gov under opportunity number RFA-NS-27-007. The call is relevant to Public housing authorities/Indian housing authorities; City or township governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; State governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Public and State controlled institutions of higher education; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses and should be reviewed on the official listing for final eligibility, forms, attachments and submission timing.

GrantResearch fundingHealth and Biomedical SciencesUnited StatesHealth
Funder
National Institutes of Health
Application deadline
Application deadline: Feb 20, 2029
Award
Up to USD 11,000,000
Applicant
Public housing authorities/Indian housing authorities; City or township governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; State governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Public and State controlled institutions of higher education; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses
Discipline
Health and Biomedical Sciences
Region
United States
Posted
Jun 16, 2026

Call summary

Overview

HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) is an official Grants.gov opportunity from National Institutes of Health. It appears under opportunity number RFA-NS-27-007 and is listed for applicants working in health and biomedical sciences.

Who can apply

Public housing authorities/Indian housing authorities; City or township governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; State governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Public and State controlled institutions of higher education; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses. Applicants should confirm all additional eligibility limits, cost-sharing rules, institutional requirements and application package instructions on the official Grants.gov page.

What it supports

  • Opportunity number: RFA-NS-27-007
  • Funding category: Health
  • Funding instrument: Cooperative Agreement

Funding and duration

Up to USD 11,000,000

Application deadline

Application deadline: Feb 20, 2029

How to apply

Open the official Grants.gov listing, review the full notice of funding opportunity and application package, then submit through the Grants.gov route specified by the agency.

Call details

Source-based overview

National Institutes of Health has posted HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional), a health and biomedical sciences funding opportunity listed on Grants.gov under opportunity number RFA-NS-27-007. The call is relevant to Public housing authorities/Indian housing authorities; City or township governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; State governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Public and State controlled institutions of higher education; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses and should be reviewed on the official listing for final eligibility, forms, attachments and submission timing.

Eligibility

Public housing authorities/Indian housing authorities; City or township governments; Independent school districts; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Special district governments; Native American tribal organizations (other than Federally recognized tribal governments); County governments; State governments; Native American tribal governments (Federally recognized); Others (see text field entitled "Additional Information on Eligibility" for clarification); Small businesses; Public and State controlled institutions of higher education; Private institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; For profit organizations other than small businesses. Applicants should confirm all additional eligibility limits, cost-sharing rules, institutional requirements and application package instructions on the official Grants.gov page.

Funding and benefits

Up to USD 11,000,000

Themes and supported activities

Opportunity number: RFA-NS-27-007

Funding category: Health

Funding instrument: Cooperative Agreement

Deadline and timeline

Application deadline: Application deadline: Feb 20, 2029.

Applicants should confirm the exact deadline time, time zone, required documents, portal steps and any institutional approvals on the official call page before submitting.

How to apply

Open the official Grants.gov listing, review the full notice of funding opportunity and application package, then submit through the Grants.gov route specified by the agency.

Before applying, check eligibility rules, budgets, attachments, page limits, partner requirements, cost-share conditions and whether the opportunity uses an expression of interest, full proposal, registration or nomination stage.