Grant opportunity

Notice of Intent to Issue NOFO DE-FOA-0003649: Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels and Feedstocks

CMEI intends to issue, on behalf of AFFO, a NOFO titled, “Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels, and Feedstocks”. This NOFO will seek applications for financial assistance awards that would support AFFO’s vision to push the frontiers of science and engineering, advance energy addition, and unleash American energy innovation. The purpose of the potential NOFO is to solicit innovative technologies that harness existing domestic biomass and pipeline resources to expand energy production and distribution. The NOFO will advance multiple alternative fuels and feedstock technology areas to maximize the benefits of these existing resources: the production of liquid intermediate products made from biomass, that are chemically, thermally, and physically stable, and that could be sold as commodities for various end applications, including for further upgrading to renewable fuels and chemicals; production of commodity chemicals and fuels at market prices from alternative feedstocks, leveraging existing refinery assets; and establishing pilot sites for blended hydrogen-natural gas that closely simulate actual gas distribution networks, to improve reliability, scalability, suitability, performance, and durability. This NOI is for informational purposes only; we are not requesting comments or applications at this time. All information provided here is subject to change. This notice serves to inform interested parties that the DOE may issue a notice of funding opportunity (NOFO). Please be aware that any future NOFO could differ significantly from what is described here, or one may not be issued at all. We will provide a designated channel for questions once a NOFO is officially released. Complete information, including the full Notice of Intent, can be found on the DOE Funding Opportunities website: https://exchange.energy.gov/.

GrantTechnology, Engineering and Artificial IntelligenceUnited StatesGolden Field OfficeGrants.gov
Funder
Golden Field Office
Applications close 2027-04-26
Applications close 2027-04-26: Apr 26, 2027
Award
USD 0
Applicant
Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"
Discipline
Technology, Engineering and Artificial Intelligence
Region
United States
Posted
Oct 27, 2026

Call summary

Overview

Notice of Intent to Issue NOFO DE-FOA-0003649: Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels and Feedstocks is an official Grants.gov notice published between 30 September and 27 October 2026. Opportunity number: DE-FOA-0003648

Who can apply

Eligible applicant types listed by the agency: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility". Applicants must also satisfy every programme-specific condition in the official notice.

What it supports

  • CMEI intends to issue, on behalf of AFFO, a NOFO titled, “Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels, and Feedstocks”. This NOFO will seek applications for financial assistance awards that would support AFFO’s vision to push the frontiers of science and engineering, advance energy addition, and unleash American energy innovation. The purpose of the potential NOFO is to solicit innovative technologies that harness existing domestic biomass and pipeline resources to expand energy production and distribution. The NOFO will advance multiple alternative fuels and feedstock technology areas to maximize the benefits of these existing resources: the production of liquid intermediate products made from biomass, that are chemically, thermally, and physically stable, and that could be sold as commodities for various end applications, including for further upgrading to renewable fuels and chemicals; production of commodity chemicals and fuels at market prices from alternative feedstocks, leveraging existing refinery assets; and establishing pilot sites for blended hydrogen-natural gas that closely simulate actual gas distribution networks, to improve reliability, scalability, suitability, performance, and durability. This NOI is for informational purposes only; we are not requesting comments or applications at this time. All information provided here is subject to change. This notice serves to inform interested parties that the DOE may issue a notice of funding opportunity (NOFO). Please be aware that any future NOFO could differ significantly from what is described here, or one may not be issued at all. We will provide a designated channel for questions once a NOFO is officially released. Complete information, including the full Notice of Intent, can be found on the DOE Funding Opportunities website: https://exchange.energy.gov/.
  • Opportunity number: DE-FOA-0003648

Funding and duration

  • Award ceiling: USD 0
  • Expected number of awards: 0

Applications close 2027-04-26

Applications close 2027-04-26: Apr 26, 2027

How to apply

Open the official Grants.gov record, review the full notice and attachments, and use the application package or agency route stated there.

Call details

Source-based overview

CMEI intends to issue, on behalf of AFFO, a NOFO titled, “Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels, and Feedstocks”. This NOFO will seek applications for financial assistance awards that would support AFFO’s vision to push the frontiers of science and engineering, advance energy addition, and unleash American energy innovation. The purpose of the potential NOFO is to solicit innovative technologies that harness existing domestic biomass and pipeline resources to expand energy production and distribution. The NOFO will advance multiple alternative fuels and feedstock technology areas to maximize the benefits of these existing resources: the production of liquid intermediate products made from biomass, that are chemically, thermally, and physically stable, and that could be sold as commodities for various end applications, including for further upgrading to renewable fuels and chemicals; production of commodity chemicals and fuels at market prices from alternative feedstocks, leveraging existing refinery assets; and establishing pilot sites for blended hydrogen-natural gas that closely simulate actual gas distribution networks, to improve reliability, scalability, suitability, performance, and durability. This NOI is for informational purposes only; we are not requesting comments or applications at this time. All information provided here is subject to change. This notice serves to inform interested parties that the DOE may issue a notice of funding opportunity (NOFO). Please be aware that any future NOFO could differ significantly from what is described here, or one may not be issued at all. We will provide a designated channel for questions once a NOFO is officially released. Complete information, including the full Notice of Intent, can be found on the DOE Funding Opportunities website: https://exchange.energy.gov/. The official record contains the controlling eligibility, budget, attachment and submission requirements for opportunity DE-FOA-0003648.

Eligibility

Eligible applicant types listed by the agency: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility". Applicants must also satisfy every programme-specific condition in the official notice.

Funding and benefits

Award ceiling: USD 0

Expected number of awards: 0

Themes and supported activities

CMEI intends to issue, on behalf of AFFO, a NOFO titled, “Leveraging Domestic Infrastructure and Resources to Unleash Alternative Chemicals, Fuels, and Feedstocks”. This NOFO will seek applications for financial assistance awards that would support AFFO’s vision to push the frontiers of science and engineering, advance energy addition, and unleash American energy innovation. The purpose of the potential NOFO is to solicit innovative technologies that harness existing domestic biomass and pipeline resources to expand energy production and distribution. The NOFO will advance multiple alternative fuels and feedstock technology areas to maximize the benefits of these existing resources: the production of liquid intermediate products made from biomass, that are chemically, thermally, and physically stable, and that could be sold as commodities for various end applications, including for further upgrading to renewable fuels and chemicals; production of commodity chemicals and fuels at market prices from alternative feedstocks, leveraging existing refinery assets; and establishing pilot sites for blended hydrogen-natural gas that closely simulate actual gas distribution networks, to improve reliability, scalability, suitability, performance, and durability. This NOI is for informational purposes only; we are not requesting comments or applications at this time. All information provided here is subject to change. This notice serves to inform interested parties that the DOE may issue a notice of funding opportunity (NOFO). Please be aware that any future NOFO could differ significantly from what is described here, or one may not be issued at all. We will provide a designated channel for questions once a NOFO is officially released. Complete information, including the full Notice of Intent, can be found on the DOE Funding Opportunities website: https://exchange.energy.gov/.

Opportunity number: DE-FOA-0003648

Deadline and timeline

Applications close 2027-04-26: Applications close 2027-04-26: Apr 26, 2027.

Applicants should confirm the exact deadline time, time zone, required documents, portal steps and any institutional approvals on the official call page before submitting.

How to apply

Open the official Grants.gov record, review the full notice and attachments, and use the application package or agency route stated there.

Before applying, check eligibility rules, budgets, attachments, page limits, partner requirements, cost-share conditions and whether the opportunity uses an expression of interest, full proposal, registration or nomination stage.