NIH Director's Transformative Research Award (R01)

Source-based overview

NIH Director's Transformative Research Award (R01) is a biomedical research award from U.S. National Institutes of Health. Supports exceptionally innovative or unconventional research projects with potential for major impact. It focuses on Transformative biomedical research; high-risk research and is relevant to United States / eligible institutions. The recorded deadline or key date is Updated 3 Sep 2026. Applicants should review the official page for the complete eligibility rules, required documents, assessment criteria, funding conditions, deadline time zone and submission route.

Eligibility

Eligible applicants and locations: United States / eligible institutions. Confirm any institutional, citizenship, career-stage and partnership requirements on the official call page.

Funding and benefits

See the official call page for funding and support details

Themes and supported activities

Transformative biomedical research; high-risk research

Biomedical Research Award

United States / eligible institutions

Deadline and timeline

Updated 3 Sep 2026: Updated 3 Sep 2026: Sep 3, 2026.

Applicants should confirm the exact deadline time, time zone, required documents, portal steps and any institutional approvals on the official call page before submitting.

How to apply

Open the official call page, confirm the current requirements and deadline time zone, prepare the requested documents and submit through the funder or organiser's stated route.

Before applying, check eligibility rules, budgets, attachments, page limits, partner requirements, cost-share conditions and whether the opportunity uses an expression of interest, full proposal, registration or nomination stage.