Grant opportunity

FY 2026 PRMRP Discovery Award

The Discovery Award backs exploratory, high-risk and potentially high-impact medical research ideas without requiring preliminary data.

GrantMedical researchDiscovery researchHigh risk high rewardUnited States
Funder
U.S. Department of Defense - Congressionally Directed Medical Research Programs
Applications close 30 July 2026
Applications close 30 July 2026: Jul 30, 2026
Award
Up to USD 385,000 over two years; approximately USD 11.165 million total
Applicant
Eligible investigators proposing innovative, high-risk research in a designated PRMRP topic area; preliminary data are not required.
Discipline
Medicine and Health Sciences
Region
United States
Posted
Jul 30, 2026

Call summary

Overview

The Discovery Award backs exploratory, high-risk and potentially high-impact medical research ideas without requiring preliminary data.

Who can apply

Eligible investigators proposing innovative, high-risk research in a designated PRMRP topic area; preliminary data are not required.

What it supports

  • Exploratory biomedical research.
  • High-risk, high-reward ideas.
  • PRMRP-designated research topics.

Funding and duration

  • About 29 awards are anticipated.
  • Direct costs may reach USD 385,000 over two years.

Applications close 30 July 2026

Applications close 30 July 2026: Jul 30, 2026

How to apply

Follow the official federal notice for the pre-application and full-application process.

Call details

Source-based overview

The Discovery Award backs exploratory, high-risk and potentially high-impact medical research ideas without requiring preliminary data. The award creates an entry point for unconventional early-stage concepts. Applicants should use the official call page for the final rules, required documents, eligible costs and submission route.

Eligibility

Eligible investigators proposing innovative, high-risk research in a designated PRMRP topic area; preliminary data are not required.

Funding and benefits

About 29 awards are anticipated.

Direct costs may reach USD 385,000 over two years.

Themes and supported activities

Exploratory biomedical research.

High-risk, high-reward ideas.

PRMRP-designated research topics.

Deadline and timeline

Applications close 30 July 2026: Applications close 30 July 2026: Jul 30, 2026.

Applicants should confirm the exact deadline time, time zone, required documents, portal steps and any institutional approvals on the official call page before submitting.

How to apply

Follow the official federal notice for the pre-application and full-application process.

Before applying, check eligibility rules, budgets, attachments, page limits, partner requirements, cost-share conditions and whether the opportunity uses an expression of interest, full proposal, registration or nomination stage.